The Blacklist Season 5's midseason premiere episode saw Elizabeth Keen (Megan Boone) returning home from the woods with revenge on her mind. She told Red (James Spader) that she was healed and back, adding, "I'm coming for Tom's killers." Red may not have killed her husband, but he and the mysterious suitcase (full of bones) are the reasons why Ian Garvey (Jonny Coyne) attacked Tom Keen (Ryan Eggold) and Liz in their house, resulting in the former's death. He died soon after figuring out the identity of the bones' owner. Liz is likely to blame Red once she discovers that. Red should be worried about Liz's determination to find Tom's killers, but he is apparently not.
James Spader told Entertainment Weekly (EW) that he does not think that his character is "feeling guilty" about being indirectly responsible for Tom Keen's death. He says that Red had warned Tom, telling him about the deadly consequences if he continued to seek the truth behind the suitcase.
"He certainly gave Tom plenty of fair warning and gave him exactly what might happen if he pursued this thing, but Tom was going to do what Tom was going to do. I think Reddington's certainly at peace with that, but it does make it fraught."