Metabolic Factors May Increase Men’s Risk Of Prostate Cancer Death

A new study shows that a man’s risk of dying from prostate cancer is higher if he suffers from high blood pressure, has a high BMI, and has high blood sugar, a condition commonly referred to as the metabolic syndrome.

Medical News Today reports the study, which appeared in the September issue of BMC Medicine, did note that obesity did not increase the risk of developing prostate cancer.

As a results of the study, the authors suggest that public health recommendations regarding lifestyle and diet, which are currently categorized to help prevent Type 2 diabetes and heart disease, be changed to include lowering the risk of prostate cancer death.

As Science Daily reports: “During an average follow-up time of 12 years, 6,673 men were diagnosed with prostate cancer and 961 died from the disease. Men in the highest categories of body mass index and blood pressure had a 36 percent and 62 percent increased risk of dying from prostate cancer, respectively.”


Though the increased metabolic factors did not lead to more cases of prostate cancer, the study appeared to find a link suggesting that, if those in the high metabolic syndrome range did develop prostate cancer, they were more likely to die from the disease.

“These observations suggest that cardiovascular risk factors such as overweight and hypertension are involved in stimulating the progression of prostate cancer,” Dr. Pär Stattin said.

Prostate cancer, according to 2011 World Health Organization statistics, is the second most common cancer among males and the sixth leading cause of cancer deaths globally among men. The reach of the disease varies around the globe however. The United States has a higher percentage of prostate cancer diagnosis than anywhere else, while it is less common in South and East Asia.