Adele last attended the music awards show in 2013 when she took home the award for Best Pop Solo Performance for her single "Set Fire to the Rain."
"I just want to send big love to all of the other girls and all of us females doing this," Adele said when accepting the award, "because we work so hard and we make it look so easy!"
One year earlier, Adele swept the Grammy Awards by taking home six awards, including Record of the Year, Best Pop Vocal Album, Best Pop Vocal Performance, and the prestigious Album of the Year award for her second studio album, 21.
"This record is inspired by something that is really normal and everyone's been through it, just a rubbish relationship," Adele said of the record at the time. "It's gone on to do things I can't tell you how I feel about it, it's been the most life-changing year."
Last year, Adele took home her 10th career Grammy for Best Song Written for Visual Media for the track "Skyfall," taken from the 2012 James Bond movie of the same name.
Although Adele didn't attend the show to pick up the award in person, the "Somebody Like You" singer instead took to Twitter to acknowledge the milestone moment.
"Wish I was there! Thank you for the grammy! (My 10th one! Whhaaa?)," Adele wrote on the social media site on January 26, "Have a wonderful night. I'm in bed, now feeling very restless."
However, despite her triumphant return to the stage this year, Adele's 25, which Forbes reported earlier this month has already sold more than 15 million copies worldwide, will not be winning any major awards on the night.
The November 20 release date of Adele's record-breaking third studio album put it outside of the 2016 eligibility period, which ended on September 30 2015. However, it is expected that the album and its singles will be nominated in a slew of categories at the 2017 ceremony.
