The Substance In Farts May Reverse Mitochondria Damage, But Years Of Research Say, ‘H2S Homeostasis Is Key’

Lightheartedly, it’s been argued that smelling farts on a regular occasion has the potential to save lives by preventing mitochondria death and cellular inflammation. Online, “Pull my finger” jokes abound. Inquisitr reported on a study published in Medicinal Chemistry Communications that asserted that the compound that makes farts stink can help cells survive and can reduce inflammation. The study says that, hydrogen sulfide, the source of the rotten egg smell in farts protects mitochondria and may help the powerhouse of cells heal. The implications for healing would include possible prevention and healing from heart attacks, stroke, ageing, MS, arthritis, diabetes, dementia and much more. Mitochondria damage is a major factor in most of today’s diseases, but actually reversing mito damage is so much more complicated than just breathing in the smell of farts.

According to Time, the researchers have developed a new compound, called AP39, that could deliver the exact right amount of the hydrogen sulfide to the exact places it’s needed within human cells. Reports are boasting cancer prevention, and the researchers feel the substance in farts, if delivered appropriately, can do more than just prevent diseases like cancer. The researchers believe that the stench in farts may be able to actually reverse mitochondria damage, but only with a little help from science. Smelling farts alone isn’t going to be enough.

Considerations about hydrogen sulfide in cell health is nothing new. Years ago, according to Phoenix Rising, Marian Dix Lemle developed a theory suggesting that the compound that makes fart stink could lie at the heart of some disease. Marian said, “…our mitochondria are descended from ancient eukaryotic cells, which appear to have retained that deep sea capability to use H2S as an energy substrate.” Marian’s theory was that a lack of Hydrogen Sulfide homeostasis within an organism is responsible for many diseases. An overload, she argued, could result in Chronic Fatigue Syndrome (CFS) in people who are hyper-sensitive to it. Hydrogen Sulfide is, interestingly, believed to play a role in the hibernation of animals. So, it’s not as simple as, “smell farts and fight disease.”

In 2009, Science News added the stinky fart compound to the list of body-friendly gasses. Research on Hydrogen Sulfide has branched out impressively from there.

For example, a lack of homeostasis of Hydrogen Sulfide within a body has been tied to some autism symptoms. According to Nature, some bacterial populations found in stool samples of ASD patients produce PPA with the help of dietary carbs. Desulfovibrio is a kind of sulfate-reducing bacteria that can produce PPA and hydrogen sulfide. The two are believed to work synergistically to cause mitochondrial dysfunction, according to Nature. Sniffing tinier farts isn’t going to alter the amount of Hydrogen Sulfide within a body.

The key that researchers have been seeking may be found because of the AP39 creation. A follow up study, which was published in The Nitric Oxide Journal, said AP39 is a “recently synthesized mitochondrially-targeted H2S donor.” That study explained, “AP39 exerted a concentration-dependent effect on mitochondrial activity.” So, don’t start sniffing farts to cure mitochondria-related disease, but do hold out hope that with each new discovery in this field, science is getting us closer to a treatment for mito disease suffers.