Khloe Kardashian Tells Selena Gomez ‘Don’t F—k With My Little Sisters’?

Khloe Kardashian issued this Twitter warning yesterday,”You want to play in the 20 year old pool… Well I’m still in my 20s & I’m better at this game than you. Don’t f**k with my little sisters!” The grapevine thinks it’s directed at Selena Gomez — Is it?

Selena Gomez’s shocking Instagram mass ‘unfollows’ began with Kylie and Kendall Jenner, but it may end with Khloe Kardashian.

Khloe, 29, punched out a tweet on April 25 to an unidentified offender.

It read: “You want to play in the 2o year old pool… Well I’m still in my 20s and I’m better at this game than you. Don’t f—k with my little sisters!

Given that headlines this week have unfavorably featured Kylie Jenner in the role of alleged ‘floozy’ with Justin Bieber while they hung out at Coachella with Kendall, Selena and others two weeks ago, and later reports of Gomez calling the sisters “toxic distractions” — lets just say we’re not surprised Big K’s come-a-knocking.

[Note: The Kylie-Justin rumor came via a UK tabloid and appear to have been dismissed by most outlets as false following reports from TMZ and E! News as to the real reason for Gomez’s Instagram purge.]

All speculative hell broke loose this past week when it was first noticed April 20 that Selena had ‘unfollowed’ Kylie and Kendall on her Instagram feed, within one week of being widely photographed partying with the Jenner girls during the first weekend of Coachella.

Underlining her split from the reality stars, Gomez also dumped her Instagram photos of the Jenners from the festival and another social occasion.

Days later, the actress-singer cut her followers to 15, shortly after unfollowing everyone.

Then, on Friday morning, TMZ reported Selena cut ties with the Jenners because she had an “epiphany” at Coachella about cleaning up her life which she kicked off by removing the allegedly “toxic” Kylie and Kendall from it.

E! News later said the same, and added Gomez’s mass Instagram eviction is all about her “reevaluating” certain relationships.

Both reports also mentioned that Selena is going to church services “almost daily.”

During a TMZ Live Talk session, Harvey Levin made the point that Gomez could have just as easily just stopped hanging with Kylie and Jenner rather than — in effect — publicly calling them out.

It’s possible this, or something like it, may also be Khloe’s view.

Wading in with her shocking tweet, it wouldn’t surprise us if we hear a little less or nothing at all about the “toxic” Jenners from Gomez’s camp next week.

After her first warning tweet, Khloe added, “If only you knew…” which Kendall retweeted.

This may give weight to the idea that Kardashian was referring to the former Disney starlet.

Incidentally, Bieber sold his home in Calabasas, California, to Khloe which just shows how connected everyone is.

But it looks like Bieber’s staying out of way on this one and has hotfooted it to New York for a photoshoot.

Do you think Khloe Kardashian intended her slam tweet for Selena Gomez, or can you think of other candidates for KhloMoney’s ire?

Selena Gomez, The Jenner Girls

(Photo: In briefly happier times.)