Cancer Cure Found For Metastasizing Cells? TRAIL Treatment 100 Percent Effective In Mice

Patrick Frye

A cancer cure may have been found metastasizing cells, with researchers at Cornell University in New York claiming their cancer treatment was 100 percent effective in mice.

As previously reported by The Inquisitr, the cancer research establishment was criticized by James Watson, discoverer of the DNA structure, and he believes taking antioxidants can actually increase the risk of cancer, not reduce it as popularly believed.

While surgery and chemotherapy are effective at treating solid tumor lumps, around 90 percent of those who die during cancer treatment do so because of metastasizing cells, which means tiny pieces of the cancer have broken off and spread to other portions of the body through the blood circulation system, creating even more tumors. So the trick to any cancer cure would be figuring out a way to prevent the spread of cancerous cells.

Normally, when cells develop defects they will often trigger apoptosis, or programmed cell death. Apoptosis can be described as the "orchestrated collapse of a cell characterized by membrane blebbing, cell shrinkage, condensation of chromatin, and fragmentation of DNA followed by rapid engulfment of the corpse by neighboring cells." In general, cancerous cells are normal body cells that have had portions of their tiny machinery break down and they're now experiencing out of control replication and growth.

Cancer researchers have long known the cell functionality related to triggering apoptosis has fallen apart. Mike King says a protein that goes by the acronym TRAIL is the key to this partial cancer cure. When TRAIL comes into contact with cancer cells, they implode.

Initial tests of this potential cancer cure were not too encouraging. When introduced into a saline solution TRAIL was only about 60 percent effective at killing cancer. But King says what was missing was blood and white blood cells for the TRAIL protein to latch onto:

"We believe the fluid forces, the pressures and forces of blood flow help give the signals to the cancer cells. So basically the fluid flow pushes the cells together, the cancer cell and the altered white cell. And so now, in the blood flow, all of your white blood cells become essentially cancer-killing machines. And whenever they bump into a cancer cell that makes its way in the circulation, that cancer cell will go on to die within a few hours."

In related news, a cancer cure drug called AMD3100, or Plerixafor, may be within 10 years of helping pancreatic cancer patients:

"We want to get the clinical trial on humans started up as soon as we can as it was so successful on mice. By enabling the body to use its own defenses to attack cancer, this approach has the potential to greatly improve treatment of solid tumors. The best possible scenario is that it will cause regression to a large proportion against pancreatic cancer. And that is not just restricted to pancreatic cancer but would be effective in many forms, including ovarian and lung cancer because they react similarly. This could potentially cure cancer, and save all those lives lost each year to the disease."