Doctors have known for quite some time that keeping Low-Density Lipoprotein or LDL (known as bad cholesterol) at low levels is good for your heart, however their original thought that raising good cholesterol (HDL) can help prevent heart disease may not be correct according to a recently study.
Published on Wednesday in medical journal The Lancet the study says there is no “direct relationship” between higher levels of HDL and a lower risk of heart attack.
According to lead researcher Dr Sekar Kathiresan from Massachusetts General Hospital:
“Ways of raising HDL cholesterol might not reduce risk of myocardial infarction.”
Dr. Kathiresan added:
“With drugs or lifestyle changes to raise HDL, we cannot automatically assume that risk of myocardial infarction will be reduced.”
While HDL has been associated with lower risk of heart attacks doctors have never been able to pin down exactly how its mechanism works to prevent heart disease and heart attacks.
To reach their conclusion scientists studied 170,000 patients and found that 15 HDL-raising genetic variants they tested did not help prevent heart attacks.
When compared to patients who did not carry the HDL elevating genes the group found nearly the same number o f heart attacks.
The studies main conclusion appears to be that heart attacks are not created by a single factor but are instead the results of multifactorial conditions that differ from one person to another.
The study is important because it could alert drug company’s to the fact that targeting LDL or HDL levels is not enough to create acceptable prescription drugs in the fight against heart attackd. According to researchers other factors should be investigated including “high blood pressure, high blood glucose, obesity and tobacco.”
Cholesterol is a soft, waxy substance. It is fatty lipid found in the body tissues and blood plasma of vertebrates (animals with bones); it is only sparingly soluble in water, but much more soluble in some organic solvents. The weak ability of cholesterol to dissolve in water is a major factor in the development of atherosclerosis, a condition associated with coronary artery disease.
cholesterol becomes bad when high levels are present. High levels in the bloodstream are associated with hardening of the arteries, premature coronary heart disease and many other vascular disease problems.
Unhealthy blood cholesterol levels are one of the major risk factors for heart disease.
When there is too much cholesterol in your blood, it builds up in the walls of your arteries, causing a process called atherosclerosis, a form of heart disease. The arteries become narrowed and blood flow to the heart muscle is slowed down or blocked. The blood carries oxygen to the heart, and if enough blood and oxygen cannot reach your heart, you may suffer chest pain. If the blood supply to a portion of the heart is completely cut off by a blockage, the result is a heart attack.
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