For years, dieters have been searching for a weight loss solution that would make shedding pounds easier. Now the Food and Drug Administration (FDA) has approved three new prescription diet drugs as well as a weight loss injectable medication. But it’s a fledgling weight loss pill that has everyone’s attention by providing a way to turn up the body’s fat-burning furnace to burn additional calories without exercise, reported the Los Angeles Times.
Fexaramine, referred to as Fex by its Salk Institute creators, will soon be in human clinical trials. When the researchers studied its effects on mice, they found that it caused the mice to use fat for fuel and burn more calories. In addition, they exhibited fewer signs of inflammation and insulin sensitivity.
Moreover, the scientists discovered that Fex caused “bad” stored white fat to change into the healthier variety that burns fat, sometimes called brown fat. Ronald Evans, director of Salk’s Gene Expression Laboratory, who authored the new study, compared the impact of Fex to eating a meal but without taking in calories.
“This pill is like an imaginary meal. It sends out the same signals that normally happen when you eat a lot of food, so the body starts clearing out space to store it. But there are no calories and no change in appetite.”
However, the Fex didn’t change the mice’s appetite. Instead, it made them more successful in burning the calories that they took in when they did eat.
How do the actions of Fex compare to a diet known for shifting the body into fat-burning mode? As the Inquisitr reported, a high-fat low-carb ketogenic diet has become the new gold standard for many weight loss gurus. They view it as the answer both for endurance athletes, such as marathon runners, and for dieters.
These types of high-fat diets are designed to burn more calories by using fat for energy, explained Colette Heimowitz, VP of Nutrition at Atkins Nutritionals.
“A low carbohydrate diet can be used to help athletes train harder, perform longer, and recover faster. Low-carb eating allows the body to burn fat for fuel.”
LeBron James used a similar low-carb diet, based on Paleo diet principles, for his weight loss success.
“I had no sugars, no dairy, I had no carbs. All I ate was meat, fish, veggies and fruit. That’s it. For 67 straight days.”
But for those who want to talk with their physicians about using a medical booster such as a diet drug, there are three currently approved FDA weight loss pills, as reported by the Inquisitr.
Those medications are Belviq, Qsymia, and Contrave. The newest addition to the line-up, Saxenda, requires an injection.
But Fex is different than the other weight loss drugs, according to io9. While the others impact various areas of the body, Fex remains in the intestine. The result is a reduction in side effects.
The laboratory studying the newest addition to the weight loss arsenal emphasized the benefits of targeting the intestine. Salks director Evans also commented on that advantage.
“When you eat, you have to quickly activate a series of responses all throughout the body,” says Evans. “And the reality is that the very first responder for all this is the intestine.”
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